Early and Menopausal Weight Gain and its Relationship with the Development of Diabetes and Hypertension

I. Rurik; C Móczár; N. Buono; T. Frese; P. Kolesnyk; J. Mahlmeister; F. Petrazzuoli; E. Pirrotta; T. Ungvári; I. Vaverkova; Z. Jancsó

doi:10.1055/s-0035-1569365

Experimental and Clinical Endocrinology & Diabetes, Table of Contents

Exp Clin Endocrinol Diabetes 2017; 125(04): 241-250
DOI: 10.1055/s-0035-1569365

Article

Early and Menopausal Weight Gain and its Relationship with the Development of Diabetes and Hypertension

I. Rurik^*

¹Department of Family and Occupational Medicine, Faculty of Public Health, University of Debrecen, Debrecen, Hungary

⁸EGPRN (European General Practice Research Network, Maastricht, The Netherlands)

⁹Primary Care Diabetes Europe Ekerem, Belgium

,

C Móczár^*

²Irinyi Primary Care Health Center, Kecskemét, Hungary

⁸EGPRN (European General Practice Research Network, Maastricht, The Netherlands)

,

N. Buono

³SNAMID (National Society of Medical Education in General Practice), Italy

⁸EGPRN (European General Practice Research Network, Maastricht, The Netherlands)

,

T. Frese

⁶Department of General Practice, University of Leipzig, Leipzig, Germany

⁸EGPRN (European General Practice Research Network, Maastricht, The Netherlands)

,

P. Kolesnyk

⁵Department of Family and Internal Medicine, Institute of Postgraduate Education and Undergraduate Training, Uzhgorod National University, Uzhgorod, Ukraine

,

J. Mahlmeister

⁶Department of General Practice, University of Leipzig, Leipzig, Germany

⁸EGPRN (European General Practice Research Network, Maastricht, The Netherlands)

,

F. Petrazzuoli

³SNAMID (National Society of Medical Education in General Practice), Italy

⁷Department of Clinical Sciences, Centre for Primary Health Care Research, Lund University, Malmö, Sweden

⁸EGPRN (European General Practice Research Network, Maastricht, The Netherlands)

,

E. Pirrotta

³SNAMID (National Society of Medical Education in General Practice), Italy

,

T. Ungvári

¹Department of Family and Occupational Medicine, Faculty of Public Health, University of Debrecen, Debrecen, Hungary

,

I. Vaverkova

⁴Slovak Society of General Practice, Slovak Medical Association, Bratislava, Slovakia

,

Z. Jancsó

¹Department of Family and Occupational Medicine, Faculty of Public Health, University of Debrecen, Debrecen, Hungary

⁹Primary Care Diabetes Europe Ekerem, Belgium

› Author Affiliations

Abstract

Background: Previous research has revealed a clear relationship between weight gain of persons and their metabolic diseases developing later. These studies have covered only short periods lasting 4–8 years.

Our goal was to collect decades’ old and often life-long anthropometric data and correlate the figures with the presence of hypertension and diabetes or both.

Methods: A retrospective international study was planned and organized to compare self-recorded data of lifelong weight gain among 60–70-year-old patients, analyze their correlation with metabolic diseases they developed, with special attention to women’s weight gain around pregnancy, delivery and menopause in primary care settings in Germany, Hungary, Italy, Slovakia and the Ukraine.

Results: Of the recruited 815 participants, 319 men and 496 women presented all the required data. Diabetics of both genders had the highest baseline weight at 20 years of age. The weight and BMI of the whole study population increased steadily until their seventies, but to a lesser extent after their fifties. Compared to the control group, changes over decades were the greatest among diabetics and also greater among patients with hypertension. Weight increase in the first decades (20–30-year-old men and 30–40-year-old women) was a significant risk factor for the development of diabetes (OR=1.044; p=0.002; 95% CI: 1.01–1.07). Among patients with diabetes and hypertension, both diagnoses were set up earlier than among those with a single morbidity.

Among females, weight increase around pregnancy and menopause correlated significantly with higher odds for the diagnoses of diabetes and/or hypertension, irrespective of the number of children.

Conclusions: During their decade-long relationship with their patients, family physicians are expected to identify the higher weight gain of their patients, especially among younger generation and intervene, if necessary.

Key words

diabetes - Germany - Hungary - hypertension - Italy - menopause - metabolic syndrome - obesity - primary care - Slovakia - the Ukraine - weight gain

Full Text

References

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